Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study

Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study

Thioredoxin-interacting protein (TXNIP) plays an important role in glucose metabolism, and its expression is regulated by DNA methylation (DNAm). Although the association between TXNIP DNAm and type 2 diabetes mellitus has been demonstrated in studies with a cross-sectional design, prospective studi...

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Main Authors: Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Yuji Hattori, Yuya Ishihara, Nobuyuki Hamajima, Shuji Hashimoto, Koji Suzuki
Format: Article
Language:English
Published: The Japan Endocrine Society 2024-06-01
Series:Endocrine Journal
Subjects:
dna methylation (dnam)
thioredoxin-interacting protein (txnip)
glucose
hemoglobin a1c (hba1c)
type 2 diabetes (t2dm)
Online Access:https://www.jstage.jst.go.jp/article/endocrj/71/6/71_EJ23-0629/_html/-char/en
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https://www.jstage.jst.go.jp/article/endocrj/71/6/71_EJ23-0629/_html/-char/en

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