Optimizing in vitro maturation of oocytes with nitric oxide-loaded microbubbles

Optimizing in vitro maturation of oocytes with nitric oxide-loaded microbubbles

IntroductionNitric oxide (NO) plays a pivotal role in female reproductive processes, yet its clinical translation is limited by its short half-life and rapid systemic clearance. This study aimed to develop a stabilized NO delivery system to enhance oocyte maturation and quality for potential applica...

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Main Authors: Lin Qiu, Qi Xu, Yi Lin, Songxue Wang, Huina Zhang, Yi Liu, Junzhao Zhao, Yingzheng Zhao, Haitao Xi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
nitric oxide
lipid microbubbles
gas-based drug delivery
oocyte
in vitro maturation
assisted reproductive technology
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1518226/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1518226/full

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