Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition

Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition

Abstract Skin photoaging results primarily from chronic ultraviolet (UV) exposure, which disrupts dermal homeostasis and promotes cellular senescence. Dermal papilla cell-conditioned medium (DPC-CM) has emerged as a promising cell-free approach for skin rejuvenation. This study aimed to explore the...

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Bibliographic Details
Main Authors: Zha Ru, Yu Wu, Qian Qu, Yong Miao, Lei Zhu, Zhiqi Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Dermal papilla cells
Conditioned medium
Skin fibroblasts
Ferroptosis
UVA
Photoaging
Online Access:https://doi.org/10.1038/s41598-025-08968-2
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https://doi.org/10.1038/s41598-025-08968-2

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