Next-generation sequencing reveals viral aetiologies of encephalitis in Ghana: a prospective cross-sectional study

Next-generation sequencing reveals viral aetiologies of encephalitis in Ghana: a prospective cross-sectional study

Abstract In Ghana, cerebrospinal fluid polymerase chain reaction (PCR) is the primary diagnostic tool for viral encephalitis. However, its application remains limited, and diagnosis is predominantly syndromic. Current data on encephalitis in Ghana are sparse and often restricted to sporadic cases, w...

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Main Authors: Richmond Yeboah, Richmond Gorman, Philip El-Duah, James Osei-Mensa, Henry Kyeremateng Acheampong, Emmanuella Nyarko-Afriyie, Michael Owusu, Yaw Ampem Amoako, Kwasi Obiri-Danso, Richard Odame Phillips, Victor Max Corman, Christian Drosten, Augustina Angelina Sylverken
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Infectious Diseases
Subjects:
Viral encephalitis
Cerebrospinal fluids
Next generation sequencing
Herpesviruses
Human immunodeficiency virus
Co-infection
Online Access:https://doi.org/10.1186/s12879-025-11436-x
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https://doi.org/10.1186/s12879-025-11436-x

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