Influenza virus drug resistance: a time-sampled population genetics perspective.

Influenza virus drug resistance: a time-sampled population genetics perspective.

The challenge of distinguishing genetic drift from selection remains a central focus of population genetics. Time-sampled data may provide a powerful tool for distinguishing these processes, and we here propose approximate Bayesian, maximum likelihood, and analytical methods for the inference of dem...

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Main Authors: Matthieu Foll, Yu-Ping Poh, Nicholas Renzette, Anna Ferrer-Admetlla, Claudia Bank, Hyunjin Shim, Anna-Sapfo Malaspinas, Gregory Ewing, Ping Liu, Daniel Wegmann, Daniel R Caffrey, Konstantin B Zeldovich, Daniel N Bolon, Jennifer P Wang, Timothy F Kowalik, Celia A Schiffer, Robert W Finberg, Jeffrey D Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004185&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004185&type=printable

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