Deciphering highly potent natural abscisic acid agonists for binding to pyrabactin resistance 1 receptor through computational approaches

Abstract Abscisic acid (ABA) agonists bind to the same receptors as ABA in plant cells and exhibit similar physiological effects. Even though synthetic ABA agonists like Pyrabactin, Quinabactin, Cyanabactin, and Opabactin can bind to the PYR1 receptor, no plant-derived natural ABA agonists have been...

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Main Authors: Pallavi M. Shanthappa, H.G. Gowtham, Poojitha B. Sridhara Setty, Saleh S. Alhewairini, Jayanthi Barasarathi, Pallavi Singh, M. Murali, Riyaz Sayyed, Shiva Prasad Kollur
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-07113-3
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