Significant PK variability of plasma-derived FIX concentrates in chinese children with Haemophilia B: A fixed single-dose study of factor IX-CTBB

Significant PK variability of plasma-derived FIX concentrates in chinese children with Haemophilia B: A fixed single-dose study of factor IX-CTBB

Background: The pharmacokinetics (PK) characters of plasma-derived Factor IX (pdFIX) concentrate in Chinese children with Haemophilia B(HB) have not yet been reported. Aim: To assess the PK parameters of pdFIX in children with severe HB and identify factors that influence FIX PK. Methods: This non-r...

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Bibliographic Details
Main Authors: Guoqing Liu, Di Ai, Gang Li, Yingzi Zhen, Xinyi Wu, Wanru Yao, Yunyun Wei, Zekun Li, Yaohan Zhou, Runhui Wu, Zhenping Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Global Medical Genetics
Subjects:
Haemophilia B
Pharmacokinetics
Children
Plasma-derived FIX
Online Access:http://www.sciencedirect.com/science/article/pii/S2699940425000414
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