Evaluating the Anti-inflammatory Efficacy of Steroids, COX-2 Selective, and Nonselective NSAIDs in Contusion Spinal Cord Injury: An Experimental Analysis

Evaluating the Anti-inflammatory Efficacy of Steroids, COX-2 Selective, and Nonselective NSAIDs in Contusion Spinal Cord Injury: An Experimental Analysis

Context: The inclusion of an anti-inflammatory agent shall be inevitable in a combinatorial approach toward treating spinal cord injury (SCI). However, the best among the commonly used anti-inflammatory agents, namely, steroids, nonsteroidal anti-inflammatory drugs (NSAIDs), and cyclooxygenases-2 (C...

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Main Authors: Sreelakshmi Kokkatt Balachandran, Krithika Iyer, Sowbarnika Arul Senthil, Akshaya Priya Ramalingam, Sankar Venkatachalam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
anti-inflammatory drugs
contusion model
cytokines
neuroinflammation
spinal cord injury
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_604_25
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