Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex
Abstract Clinical translation of tissue-engineered advanced therapeutic medicinal products is hindered by a lack of patient-dependent and independent in-process biological quality controls that are reflective of in vivo outcomes. Recent insights into the mechanism of native bone repair highlight a r...
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| Main Authors: | Isaak Decoene, Hanna Svitina, Mohamed Belal Hamed, Anastassios Economou, Steve Stegen, Frank P. Luyten, Ioannis Papantoniou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-03-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-025-00418-z |
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