Self-assembly cloning: a rapid construction method for recombinant molecules from multiple fragments

Enzyme-free cloning (EFC) can rapidly produce an in-frame fusion gene with multiple fragments. To practically apply EFC, we investigated the extent and sequence of complementary staggered overhangs necessary to direct self-assembly of multiple fragments as well as a size limitation of the constructe...

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Bibliographic Details
Main Authors: Akira Matsumoto, Taichi Q. Itoh
Format: Article
Language:English
Published: Taylor & Francis Group 2011-07-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/000113705
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