E46K α-Synuclein Mutation Fails to Promote Neurite Outgrowth by Not Inducing Cdc42EP2 Expression, Unlike Wild-Type or A53T α-Synuclein in SK-N-SH Cells
Background/Objectives: α-Synuclein (α-syn) protein is a major pathological agent of familial Parkinson’s disease (PD), and its levels and aggregations determine neurotoxicity in PD pathogenesis. Although the pathophysiological functions of α-syn have been extensively studied, its biological function...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-12-01
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Series: | Brain Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3425/15/1/9 |
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