Matrix Metalloproteinases: Pathophysiologic Implications and Potential Therapeutic Targets in Cardiovascular Disease

Matrix Metalloproteinases: Pathophysiologic Implications and Potential Therapeutic Targets in Cardiovascular Disease

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play a crucial role in extracellular matrix (ECM) remodeling and are implicated in the pathogenesis of various cardiovascular diseases (CVDs). Their dysregulation has been linked to atherosclerosis, myocardial infarc...

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Bibliographic Details
Main Authors: Daniela Maria Tanase, Emilia Valasciuc, Ioana-Bianca Anton, Evelina Maria Gosav, Nicoleta Dima, Andrei Ionut Cucu, Claudia Florida Costea, Diana Elena Floria, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Manuela Ciocoiu, Mariana Floria
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
Subjects:
matrix metalloproteinases
MMPs
cardiovascular disease
CVDs
atherosclerosis
heart failure
Online Access:https://www.mdpi.com/2218-273X/15/4/598
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