Comprehensive analysis of PIK3CA mutations in advanced colorectal cancer using circulating tumor DNA profiling
Abstract Mutations in PIK3CA are prevalent in advanced colorectal cancer (CRC) and are associated with advanced-stage disease and poor prognosis. However, the prognostic value of these mutations remains unclear. To better understand their role in CRC progression, we evaluated the genomic landscape o...
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| Main Authors: | Allante Milsap, Jill Tsai, Baqir Jafry, Alex Kim, Syed Mohammad Ali Kazmi, Nilesh Verma |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-00975-w |
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