Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome

Background Breast cancer (BC) progression to metastatic disease is the leading cause of death in women worldwide. Metastasis is driven by cancer stem cells (CSCs) and signals from their microenvironment. Interleukin (IL) 30 promotes BC progression, and its expression correlates with disease recurren...

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Bibliographic Details
Main Authors: Carlo Sorrentino, Paola Lanuti, Emma Di Carlo, Alice Turdo, Matilde Todaro, Stefania Livia Ciummo, Luigi D'Antonio, Cristiano Fieni
Format: Article
Language:English
Published: BMJ Publishing Group 2021-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/10/e002966.full
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