Multifunctional hyaluronic acid-based biomimetic/pH-responsive hybrid nanostructured lipid carriers for treating bacterial sepsis

Multifunctional hyaluronic acid-based biomimetic/pH-responsive hybrid nanostructured lipid carriers for treating bacterial sepsis

Abstract Introduction The application of biomimetic and stimuli-responsive nanocarriers displays considerable promise in improving the management of bacterial sepsis and overcoming antimicrobial resistance. Therefore, the study aimed to synthesize a novel hyaluronic acid-lysine conjugate (HA-Lys) an...

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Bibliographic Details
Main Authors: Eman Elhassan, Calvin A. Omolo, Mohammed A. Gafar, Eman A. Ismail, Usri H. Ibrahim, Rene Khan, Mathieu Lesouhaitier, Paul Kubes, Thirumala Govender
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Biomedical Science
Subjects:
Biomimetic
PH-responsive
Hyaluronic acid-lysine
Hybrid nanocarriers
Bacterial sepsis
Antibiotic delivery
Online Access:https://doi.org/10.1186/s12929-024-01114-6
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https://doi.org/10.1186/s12929-024-01114-6

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