Immunostimulatory DNA Tetrahedron‐Based Nanovaccine Combined With Immune Checkpoint PD‐1 Blockade for Boosting Systemic Immune Responses Against Oral Squamous Cell Carcinoma

Immunostimulatory DNA Tetrahedron‐Based Nanovaccine Combined With Immune Checkpoint PD‐1 Blockade for Boosting Systemic Immune Responses Against Oral Squamous Cell Carcinoma

ABSTRACT Despite advancements in immune checkpoint blockade (ICB) therapies for treating various tumors, the immunosuppressive environment in oral squamous cell carcinoma (OSCC) significantly limits therapeutic efficacy. Tumor vaccines, which offer great potential for cancer immunotherapy, still fac...

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Bibliographic Details
Main Authors: Xueting Yang, Yun Wang, Yan Yang, Sicheng Zhang, Dianri Wang, Yi Luo, Chunyan Shui, Yongcong Cai, Ruoyi Yang, Shuang Dong, Mu Yang, Yunfeng Lin, Chao Li
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Aggregate
Subjects:
immune checkpoint blockade
nanovaccines
oral squamous cell carcinoma
tetrahedral framework nucleic acids
tumor immunotherapy
Online Access:https://doi.org/10.1002/agt2.70061
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https://doi.org/10.1002/agt2.70061

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