Lactylation prognostic signature identifies DHCR7 as a modulator of chemoresistance and immunotherapy efficacy in bladder cancer

Lactylation prognostic signature identifies DHCR7 as a modulator of chemoresistance and immunotherapy efficacy in bladder cancer

BackgroundBladder cancer (BLCA), the 10th most common cancer worldwide, presents a worsening prognosis as the disease progresses. Reliable tools for predicting BLCA prognosis and treatment efficacy remain urgently needed.MethodsExpression profiles of lactylation related genes were analyzed utilizing...

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Bibliographic Details
Main Authors: Yuanqiao Zhao, Zhuo Xing, Yongqi Zhao, Haozhe Xu, Ruilin Liu, Tiejun Yang, Yinhuai Wang, Xuan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
bladder cancer
lactylation
chemotherapy
Dhcr7
immunotherapy
prognostic signature
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585727/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585727/full

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