Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy

Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy

<b>Background:</b> Rheumatoid arthritis (RA) is a debilitating autoimmune disorder characterized by chronic inflammation and joint damage. Despite advancements in treatment, complete remission remains elusive. <b>Methods:</b> In this study, we introduce a novel lipid nanopart...

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Bibliographic Details
Main Authors: Yanru Feng, Xintong Pan, Ziqian Li, Yue Li, Ya’nan Sun, Shaokun Yang, Chaoxing He, Yunjie Dang, Lu Huang, Bai Xiang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
lipid nanoparticle
co-delivery
hydroxychloroquine
si<i>TNF-α</i>
rheumatoid arthritis
Online Access:https://www.mdpi.com/1999-4923/17/1/45
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