Attenuation of neutrophil adhesion and formation of neutrophil extracellular traps by pooled human immune globulins

Attenuation of neutrophil adhesion and formation of neutrophil extracellular traps by pooled human immune globulins

IntroductionThis study investigated the efficacy of pooled human immune globulins (Flebogamma® DIF) to combat the formation of neutrophil extracellular traps (NETs) and NETosis, along with neutrophil adhesion to corneal epithelial cells in response to dry eye disease relevant stimuli.MethodsHuman ne...

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Bibliographic Details
Main Authors: Vidhya R. Rao, Sana Iqbal, Bradford A. Young, Christine Mun, Sandeep Jain, Simon Kaja
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
ocular surface disease
dry eye disease
anti-citrullinated protein autoantibodies
neutrophil extracellular trap
pooled human immune globulin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1465776/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1465776/full

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