Neutralizing Antibody Screening Using NanoBiT-Based Virus-like Particles of Foot-and-Mouth Disease Type Asia1 Enhances Biosafety and Sensitivity

Neutralizing Antibody Screening Using NanoBiT-Based Virus-like Particles of Foot-and-Mouth Disease Type Asia1 Enhances Biosafety and Sensitivity

Background/Objectives: Foot-and-mouth disease (FMD) is a highly contagious class 1 animal disease that affects cloven-hoofed animals, such as cattle, pigs, and goats. Diagnosis and research on live FMD virus (FMDV) typically require biosafety level 3 facilities, which are challenging to maintain due...

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Main Authors: Hyejin Kim, Dong-Wan Kim, Giyoun Cho, Ji-Hyeon Hwang, Yeonrae Chae, Taejun Kim, Jae Young Kim, Young-Joon Ko, Jong-Hyeon Park, Yoon-Hee Lee, Sung-Han Park
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Viruses
Subjects:
foot-and-mouth disease
virus-like particles
NanoBiT assay
HiBiT
LgBiT
Online Access:https://www.mdpi.com/1999-4915/17/3/337
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