Identification of vitronectin as a potential non-invasive biomarker of metastatic breast cancer using a label-free LC–MS/MS approach

Identification of vitronectin as a potential non-invasive biomarker of metastatic breast cancer using a label-free LC–MS/MS approach

Abstract Background Breast cancer (BC) is a complex heterogenous disease that is a leading cause of death in women. For patients with early stage disease following primary BC therapy, approximately 30% will develop metastatic BC (MBC). The median survival of MBC patients is ~ 2–3 yr. While the early...

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Main Authors: Roopali Roy, Elisa M. Schunkert, Petra Olivova, Martin Gilar, Scott Geromanos, Guo-Zhong Li, John Gebler, Adelle Dagher, Andrew El-Hayek, Rama Aldakhlallah, Steven J. Staffa, David Zurakowski, Margaret Lotz, Susan Pories, Marsha A. Moses
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Breast Cancer Research
Subjects:
Liquid chromatography with tandem mass spectrometry (LC–MS/MS)
REMARK
Urinary biomarkers
Metastatic breast cancer
Surveillance
Vitronectin
Online Access:https://doi.org/10.1186/s13058-025-02053-2
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https://doi.org/10.1186/s13058-025-02053-2

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