Effect of lacosamide on cortical spreading depolarization in mice

Abstract Background Antiseizure medications are often used as preventive treatment of migraine in appropriate cases; however, the efficacy of lacosamide (LCM), a sodium channel blocker, in preventing migraine attacks remains unclear. Cortical spreading depolarization (CSD) refers to a wave of slowly...

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Bibliographic Details
Main Authors: Chisato Iba, Miyuki Unekawa, Keiko Ihara, Yoshikane Izawa, Jin Nakahara, Tsubasa Takizawa
Format: Article
Language:English
Published: BMC 2025-07-01
Series:The Journal of Headache and Pain
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Online Access:https://doi.org/10.1186/s10194-025-02099-9
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