Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation

A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid...

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Bibliographic Details
Main Authors: Silje Johansen, Jostein Kråkenes, C. A. Vedeler, Anette Margrethe Storstein, Håkon Reikvam
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2022/4174755
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Summary:A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination revealed findings suspicious for limbic encephalitis (LE), successfully treated with intravenous immunoglobulins and intravenous corticosteroids. Although a rare complication after allo-HSCT, physicians should be aware of neurological symptoms that develop throughout the transplantation course.
ISSN:2090-6617