Physiological and pathophysiological effects of L-tryptophan’s metabolites on the brain and immunity – a challenge for drug development

The dysregulation of the kynurenine branch from tryptophan (TRP) metabolism can cause an imbalance between neuroprotective kynurenic acid and neurotoxic kynurenine metabolites in some psychiatric and neurodegenerative disorders. Therefore, the modulation of TRP metabolism may contribute to novel the...

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Bibliographic Details
Main Authors: Petar Iliev, Simeon Ivanov, Simeon Lazarov, Georgeta Bocheva
Format: Article
Language:English
Published: Pensoft Publishers 2025-03-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/148033/download/pdf/
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