Mycobacterial PstP impairs host RNA alternative splicing by dephosphorylation of spliceosome RBMX at S189

Mycobacterial PstP impairs host RNA alternative splicing by dephosphorylation of spliceosome RBMX at S189

Abstract Mycobacterium tuberculosis (Mtb) infection significantly alters host cellular signaling and protein functions, facilitating immune evasion and intracellular survival. However, the molecular mechanisms underlying these interactions remain incompletely characterized. Here, we employed a multi...

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Bibliographic Details
Main Authors: Tianxian Liu, Jun‐Yu Xu, Lei Zhao, Yameng Fan, Shuyu Xie, Ke Ma, Ying Zhou, Minjia Tan, Bang‐Ce Ye
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:iMetaOmics
Subjects:
inflammatory response
integrative multi‐omic analysis
mycobacteria
PLA2G7
RBMX S189
RNA alternative splicing
Online Access:https://doi.org/10.1002/imo2.53
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https://doi.org/10.1002/imo2.53

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