Analysis of post-transcriptional regulatory signatures and immune cell subsets in premature ovarian insufficiency based on full-length transcriptome

Analysis of post-transcriptional regulatory signatures and immune cell subsets in premature ovarian insufficiency based on full-length transcriptome

Abstract Premature ovarian insufficiency (POI) is a reproductive endocrine disorder characterized by infertility and the perimenopausal syndrome. Its genetic etiology is highly heterogeneous and not yet fully understood. Limited by short-read sequencing, the profile and structural variation of the f...

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Bibliographic Details
Main Authors: Zhaoyang Yu, Xiqian Zhang, Yingqi Nong, Hongfan Ding, Xiaoqian Fu, Feiwen Li, Lidan Liu, Mujun Li, Weilong Peng, Huimei Wu, Fenghua Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Premature ovarian insufficiency
Full-length transcriptome
Alternative splicing
Alternative polyadenylation
Immune cell subtypes
Online Access:https://doi.org/10.1038/s41598-025-89391-5
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https://doi.org/10.1038/s41598-025-89391-5

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