Effects of serial passaging of field isolates of Bangladeshi PPR virus in Vero cells on the fusion protein

Effects of serial passaging of field isolates of Bangladeshi PPR virus in Vero cells on the fusion protein

Abstract Objectives Fusion (F) protein is crucial for facilitating viral entry into host cells and contributes to the virulence of Morbilliviruses. Serial passaging of the Peste Des Petits Ruminants virus (PPRV) in nonnative hosts can lead to mutations that potentially reduce pathogenicity. Hence, t...

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Bibliographic Details
Main Authors: Md. Saiful Islam Siddiqui, Anja Globig, Md. Mushfiqur Rahman, Md. Rafiqul Islam, Emdadul Haque Chowdhury
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Irish Veterinary Journal
Subjects:
Continual passaging
Virus
Cell culture
Fusion protein
Nucleotide sequence
Online Access:https://doi.org/10.1186/s13620-025-00298-z
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https://doi.org/10.1186/s13620-025-00298-z

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