Causal Relationships Between the Gut Microbiota, Inflammatory Cytokines, and Amyotrophic Lateral Sclerosis: A Mendelian Randomization Analysis

Causal Relationships Between the Gut Microbiota, Inflammatory Cytokines, and Amyotrophic Lateral Sclerosis: A Mendelian Randomization Analysis

ABSTRACT Background The relationship between gut microbiota (GM) and amyotrophic lateral sclerosis (ALS) is well‐documented. However, the causal nature of this association and the potential mediating role of inflammatory cytokines (ICs) have yet to be elucidated. Methods We performed Mendelian rando...

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Bibliographic Details
Main Authors: Li Changqing, Yu Leying, Ma Caiyun, Wen Hebao, Han Laiguo, Zhao Xiaojiang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Brain and Behavior
Subjects:
Gut microbiota
Amyotrophic Lateral Sclerosis
inflammatory cytokines
Mendelian randomization
Online Access:https://doi.org/10.1002/brb3.70571
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https://doi.org/10.1002/brb3.70571

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