Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β

Hepatoprotective potential of Chrysin in a rat model of isoniazid- and rifampicin-induced hepatic injury: suppression of matrix metalloproteinase and transforming growth factor β

Abstract Background The ability of Chrysin (CHY) to scavenge free radicals has been widely explored. The scope of the research was to show that CHY protects the rat liver against damage caused by the drugs isoniazid (INH) and rifampicin (RFM). Results Rats were divided into 6 groups, each of which h...

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Bibliographic Details
Main Authors: Deepa Mandlik, Akhilesh Tokey, Rohit Lokhande, Yash Dagadu, Heena Choudhary, Satish Mandlik
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Isoniazid
Rifampicin
Chrysin
Silymarin
Oxidative stress
Hepatoprotective
Online Access:https://doi.org/10.1186/s43094-025-00766-x
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