Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of met...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/9071097 |
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| _version_ | 1832562285996933120 |
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| author | Marta Gonzalez Rozas Lidia Hernanz Roman Diego Gonzalez Gonzalez José Luis Pérez-Castrillón |
| author_facet | Marta Gonzalez Rozas Lidia Hernanz Roman Diego Gonzalez Gonzalez José Luis Pérez-Castrillón |
| author_sort | Marta Gonzalez Rozas |
| collection | DOAJ |
| description | Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism. |
| format | Article |
| id | doaj-art-c6d3f4f0a4af4da49d92766eb3e1f652 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-c6d3f4f0a4af4da49d92766eb3e1f6522025-02-03T01:23:05ZengWileyCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/90710979071097Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver CirrhosisMarta Gonzalez Rozas0Lidia Hernanz Roman1Diego Gonzalez Gonzalez2José Luis Pérez-Castrillón3Internal Department, Hospital de Segovia, Segovia, SpainInternal Department, Hospital Universitario Río Hortega, Valladolid, SpainPathology Department, Hospital Universitario Río Hortega, Valladolid, SpainInternal Department, Hospital Universitario Río Hortega, Valladolid, SpainStudies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism.http://dx.doi.org/10.1155/2016/9071097 |
| spellingShingle | Marta Gonzalez Rozas Lidia Hernanz Roman Diego Gonzalez Gonzalez José Luis Pérez-Castrillón Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis Case Reports in Endocrinology |
| title | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis |
| title_full | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis |
| title_fullStr | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis |
| title_full_unstemmed | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis |
| title_short | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis |
| title_sort | panhypopituitarism due to absence of the pituitary stalk a rare aetiology of liver cirrhosis |
| url | http://dx.doi.org/10.1155/2016/9071097 |
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