Cocaine-induced gene regulation in D1 and D2 neuronal ensembles of the nucleus accumbens

Abstract Cocaine use disorder is characterized by persistent drug-seeking behavior and a high risk of relapse, driven in part by lasting molecular and circuit adaptations in the nucleus accumbens. To explore the transcriptomic changes underlying these alterations, we employed fluorescence-activated...

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Bibliographic Details
Main Authors: Philipp Mews, Autumn VA Mason, Emily G. Kirchner, Molly Estill, Eric J. Nestler
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08327-x
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