Evolutionary divergence of induced versus constitutive antiviral gene expression levels between primates and rodents.

Hundreds of genes are upregulated in response to pathogen infection. These genes' sequences often diverge across mammals, to counteract rapid pathogen evolution. However, the transcriptional divergence of these genes, their relative levels before and after infection in different host species, r...

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Bibliographic Details
Main Authors: Lilach Schneor, Dafna Tussia-Cohen, Evgeny Fraimovitch, Sivan Friedman, Tzachi Hagai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013165
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