Regulation of Senescence in Cancer and Aging

Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative stress. This stress response has an antagonistically pleiotropic effect to organisms: beneficial as a tumor suppressor, but detrimental by c...

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Bibliographic Details
Main Authors: Yahui Kong, Hang Cui, Charusheila Ramkumar, Hong Zhang
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.4061/2011/963172
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