Novel bi-allelic variants in DNAH10 lead to multiple morphological abnormalities of sperm flagella and male infertility

Novel bi-allelic variants in DNAH10 lead to multiple morphological abnormalities of sperm flagella and male infertility

Multiple morphological abnormalities of sperm flagella (MMAF) is a severe form of asthenoteratozoospermia, characterized by morphological abnormalities and reduced motility of sperm, causing male infertility. Although approximately 60% of MMAF cases can be explained genetically, the etiology of the...

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Main Authors: Muhammad Shoaib, Muhammad Zubair, Wasim Shah, Meftah Uddin, Ansar Hussain, Ghulam Mustafa, Fazal Rahim, Huan Zhang, Imtiaz Ali, Tanveer Abbas, Yousaf Raza, Sui-Xing Fan, Qing-Hua Shi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Asian Journal of Andrology
Subjects:
asthenoteratozoospermia
dnah10
male infertility
multiple morphological abnormalities of sperm flagella
Online Access:https://journals.lww.com/10.4103/aja2024116
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