Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report

Introduction: Ludwig angina is a potentially fatal condition characterized by soft tissue infection of the submandibular, sublingual, and submental compartments. Pseudo-Ludwig angina is a rare condition characterized by sublingual swelling of non-infectious etiology, typically in the setting of supr...

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Main Authors: Utku Ekin, Arham Hazari, Nizar Alyassin, Alan Alcantara, Moh’d Hazem Azzam, Mourad Ismail
Format: Article
Language:English
Published: eScholarship Publishing, University of California 2025-01-01
Series:Clinical Practice and Cases in Emergency Medicine
Online Access:https://escholarship.org/uc/item/93v8g0kz
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author Utku Ekin
Arham Hazari
Nizar Alyassin
Alan Alcantara
Moh’d Hazem Azzam
Mourad Ismail
author_facet Utku Ekin
Arham Hazari
Nizar Alyassin
Alan Alcantara
Moh’d Hazem Azzam
Mourad Ismail
author_sort Utku Ekin
collection DOAJ
description Introduction: Ludwig angina is a potentially fatal condition characterized by soft tissue infection of the submandibular, sublingual, and submental compartments. Pseudo-Ludwig angina is a rare condition characterized by sublingual swelling of non-infectious etiology, typically in the setting of supratherapeutic anticoagulation. However, other etiologies, such as angioedema and trauma, have been described. Case Report: We present the case of a 59-year-old female with pseudo-Ludwig angina that developed in the setting of warfarin therapy and supratherapeutic international normalized ratio. She presented with sublingual swelling and dysphagia. She was successfully treated with dexamethasone, vitamin K, and fresh frozen plasma. The most appropriate imaging modalities in these cases are contrast-enhanced computed tomography (CT) and CT angiogram. If a hematoma is present, antibiotics for anaerobic coverage are also appropriate. Conclusion: We hope this case sheds light upon this rare pathology and ultimately hastens recognition and proper intervention.
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institution Kabale University
issn 2474-252X
language English
publishDate 2025-01-01
publisher eScholarship Publishing, University of California
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series Clinical Practice and Cases in Emergency Medicine
spelling doaj-art-c6926e73c3e44dd3b22018f86d1dd45b2025-02-04T17:35:19ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2025-01-0191909410.5811/cpcem.20386cpcem-9-90Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case ReportUtku Ekin0Arham Hazari1Nizar Alyassin2Alan Alcantara3Moh’d Hazem Azzam4Mourad Ismail5St. Joseph’s University Medical Center, Department of Pulmonary and Critical Care Medicine, Paterson, New JerseySt. Joseph’s University Medical Center, Department of Pulmonary and Critical Care Medicine, Paterson, New JerseySt. Joseph’s University Medical Center, Department of Internal Medicine, Paterson, New JerseySt. Joseph’s University Medical Center, Department of Internal Medicine, Paterson, New JerseySt. Joseph’s University Medical Center, Department of Pulmonary and Critical Care Medicine, Paterson, New JerseySt. Joseph’s University Medical Center, Department of Pulmonary and Critical Care Medicine, Paterson, New JerseyIntroduction: Ludwig angina is a potentially fatal condition characterized by soft tissue infection of the submandibular, sublingual, and submental compartments. Pseudo-Ludwig angina is a rare condition characterized by sublingual swelling of non-infectious etiology, typically in the setting of supratherapeutic anticoagulation. However, other etiologies, such as angioedema and trauma, have been described. Case Report: We present the case of a 59-year-old female with pseudo-Ludwig angina that developed in the setting of warfarin therapy and supratherapeutic international normalized ratio. She presented with sublingual swelling and dysphagia. She was successfully treated with dexamethasone, vitamin K, and fresh frozen plasma. The most appropriate imaging modalities in these cases are contrast-enhanced computed tomography (CT) and CT angiogram. If a hematoma is present, antibiotics for anaerobic coverage are also appropriate. Conclusion: We hope this case sheds light upon this rare pathology and ultimately hastens recognition and proper intervention.https://escholarship.org/uc/item/93v8g0kz
spellingShingle Utku Ekin
Arham Hazari
Nizar Alyassin
Alan Alcantara
Moh’d Hazem Azzam
Mourad Ismail
Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
Clinical Practice and Cases in Emergency Medicine
title Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
title_full Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
title_fullStr Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
title_full_unstemmed Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
title_short Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
title_sort successful management of pseudo ludwig angina from supratherapeutic warfarin use a case report
url https://escholarship.org/uc/item/93v8g0kz
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