Tocotrienol suppresses colitis-associated cancer progression through TLR4 signaling in a mouse model of colorectal cancer

This study aimed to evaluate the preventive efficacy of tocotrienol in inhibiting the nuclear factor-kappa B (NF-κB) mediated inflammation pathways in colorectal cancer. We utilized the azoxymethane (AOM) and dextran sulfate sodium salt (DSS) to induce colitis-associated colorectal cancer (CAC) mice...

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Bibliographic Details
Main Authors: Qian Li, Shujing Zhang, Qinghong Zhou, Chenxi Gu, Yinghua Liu, Jing Zhang, Jingshu Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Toxicology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X24000495
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