Activation of estrogen-responsive genes does not require their nuclear co-localization.

The spatial organization of the genome in the nucleus plays a role in the regulation of gene expression. Whether co-regulated genes are subject to coordinated repositioning to a shared nuclear space is a matter of considerable interest and debate. We investigated the nuclear organization of estrogen...

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Bibliographic Details
Main Authors: Silvia Kocanova, Elizabeth A Kerr, Sehrish Rafique, Shelagh Boyle, Elad Katz, Stephanie Caze-Subra, Wendy A Bickmore, Kerstin Bystricky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000922&type=printable
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