Sodium aescinate protects renal ischemia-reperfusion and pyroptosis through AKT/NLRP3 signaling pathway

Sodium aescinate protects renal ischemia-reperfusion and pyroptosis through AKT/NLRP3 signaling pathway

Renal ischemia-reperfusion injury (RIRI) is a common cause of acute renal injury. Studies have shown that sodium aescinate (SA) may serve as a potential therapeutic agent, although its exact mechanism remains unclear. This study first evaluated the efficacy of SA using a mouse renal ischemia-reperfu...

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Bibliographic Details
Main Authors: Liu Xin, Ning Kanghao, Li Jiacheng, Yan Xiaodong, Yan Juhan, Zhao Xinyang, Li Xiangdong
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Kidney ischemia-reperfusion injury
pyroptosis
sodium aescinoside
AKT/NLRP3 signaling
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2488140
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2488140

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