Altered levels of angiogenin and tRNA-derived fragments associate with severe asthma

Altered levels of angiogenin and tRNA-derived fragments associate with severe asthma

Abstract Recent discoveries highlight angiogenin (ANG) and 5’ tRNA-derived fragments as key factors in stress response and cell survival. To explore their role in asthma pathogenesis, particularly in severe cases, we evaluated the levels of ANG and 5’ tRNA halves (tRHs) derived from tRNA Glu (5'...

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Main Authors: Clara Claus, Julieta B. Grosso, María Belen Maraval, Matias Ardusso, Oscar A. Bottasso, Tania Maes, Ken Bracke, Guy Brusselle, Mauro Ibañez, Ledit R. F. Ardusso, Silvana V. Spinelli
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Asthma
Angiogenin
tRNA-derived fragments
tRH
Stress
Online Access:https://doi.org/10.1038/s41598-025-03314-y
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https://doi.org/10.1038/s41598-025-03314-y

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