Acute stimulation of glucose metabolism by H2O2 sustains the NADPH steady-state under oxidative stress

Oxidative stress reprograms metabolic flux from glycolysis to the pentose phosphate pathway. Recently, it has been proposed that NADPH acts as a key molecule in pentose phosphate pathway regulation by exerting negative feedback through tonic inhibition of glucose-6-phosphate dehydrogenase. Interesti...

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Bibliographic Details
Main Authors: C. Aburto, I. Ruminot, A. San Martín
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002538
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