In silico analysis of UCP promoters predicts conserved and human specific regulators of adipocyte thermogenesis

In silico analysis of UCP promoters predicts conserved and human specific regulators of adipocyte thermogenesis

Summary: Adipocyte thermogenesis is a promising therapeutic target to treat metabolic diseases. We predicted transcription factors (TFs) and response elements (REs) regulating the human UCP1 gene, a key regulator of thermogenesis, by comparing its promoter with those of UCP2 and UCP3 in humans, mice...

Full description

Saved in:
Bibliographic Details
Main Authors: Beáta B. Tóth, Géza Hegedűs, Eszter Virág, Gergely Tamás Pethő, Levente Laczkó, László Fésüs
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Genomic analysis
Sequence analysis
Sequence homology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225012301
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2589004225012301

Similar Items