INM004: Polyclonal Neutralizing Antibodies Against Shiga Toxin as a Treatment for Hemolytic Uremic Syndrome

INM004: Polyclonal Neutralizing Antibodies Against Shiga Toxin as a Treatment for Hemolytic Uremic Syndrome

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI). Shiga toxin (Stx)-producing <i>Escherichia coli</i>-associated HUS (STEC-HUS) is one of the leading causes of AKI in childr...

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Main Authors: Marta Rivas, Mariana Pichel, Vanesa Zylberman, Mariana Colonna, Marina Valerio, Carolina Massa, Romina Pardo, Andrés E. Ciocchini, Santiago Sanguineti, Ian Roubicek, Linus Spatz, Fernando Alberto Goldbaum
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxins
Subjects:
Shiga toxin
hemolytic uremic syndrome
STEC-HUS
diagnosis
immunotherapy treatment
vaccine development
Online Access:https://www.mdpi.com/2072-6651/17/6/282
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