Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus
In this study, it was aimed to assess the effects ol noradrenalın on the stellate neuron Intracellular recordings were performed (rom stellate neurons ol mice cochlear nucleus in vitro using the whole cell patch clamp technique The resting potential of stellate neurons was -61.3 ± 3.3 milivolt (mV)H...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=282 |
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| author | Ramazan Bal |
| author_facet | Ramazan Bal |
| author_sort | Ramazan Bal |
| collection | DOAJ |
| description | In this study, it was aimed to assess the effects ol noradrenalın on the stellate neuron Intracellular recordings were performed (rom stellate neurons ol mice cochlear nucleus in vitro using the whole cell patch clamp technique The resting potential of stellate neurons was -61.3 ± 3.3 milivolt (mV)Hn= 18) and input resistance was 210 21 megaOhm (Mil) (n=18). Noradrenalin (100 mikro mo! (nM)) applied in perfusion solution depolarized the resting potantial by 26.1 ±4.1 rnV (n=5). In some cells, noradrenalin caused the resting potential to shift further in depolarized potentials, resulting in being spontaneously silent. The study of voltage clamp using ramp voltage protocol indicated that potassium current decreased. In conclusion, noradrenalin increases the spontaneously occurring activity, decreasing the potassium current amplitude. |
| format | Article |
| id | doaj-art-c6446162eee24069ba48009c078f0991 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-c6446162eee24069ba48009c078f09912025-01-03T01:35:56ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531745560282Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleusRamazan BalIn this study, it was aimed to assess the effects ol noradrenalın on the stellate neuron Intracellular recordings were performed (rom stellate neurons ol mice cochlear nucleus in vitro using the whole cell patch clamp technique The resting potential of stellate neurons was -61.3 ± 3.3 milivolt (mV)Hn= 18) and input resistance was 210 21 megaOhm (Mil) (n=18). Noradrenalin (100 mikro mo! (nM)) applied in perfusion solution depolarized the resting potantial by 26.1 ±4.1 rnV (n=5). In some cells, noradrenalin caused the resting potential to shift further in depolarized potentials, resulting in being spontaneously silent. The study of voltage clamp using ramp voltage protocol indicated that potassium current decreased. In conclusion, noradrenalin increases the spontaneously occurring activity, decreasing the potassium current amplitude.http://eurasianjvetsci.org/pdf.php3?id=282noradrenalincochlear nucleusmodulationintracellular recording |
| spellingShingle | Ramazan Bal Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus Eurasian Journal of Veterinary Sciences noradrenalin cochlear nucleus modulation intracellular recording |
| title | Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| title_full | Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| title_fullStr | Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| title_full_unstemmed | Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| title_short | Effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| title_sort | effects of nor adrenal in on the activity of stellate cells in mouse cochlear nucleus |
| topic | noradrenalin cochlear nucleus modulation intracellular recording |
| url | http://eurasianjvetsci.org/pdf.php3?id=282 |
| work_keys_str_mv | AT ramazanbal effectsofnoradrenalinontheactivityofstellatecellsinmousecochlearnucleus |