Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia

Foxr1 is a member of the evolutionarily conserved forkhead box (Fox) family of transcription factors, characterized by a winged-helix DNA-binding domain. We previously demonstrated that Foxr1 deletion in mice results in severe perinatal lethality, cortical thinning, and ventricular enlargement, indi...

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Bibliographic Details
Main Authors: Hannah Waxman, Marcus Kankkunen, Arya Gupta, Margo Dowgiewicz, Uwe Beffert, Angela Ho
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1589043/full
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