DAXX-dependent H3.3 deposition maintains myoblast cell identity independently of other histone chaperone complexes
Summary: H3.3 histone chaperone DAXX regulates heterochromatin silencing; however, its function in transcription regulation remains understudied. Here, we show that Daxx knockout (KO) myoblasts have impaired differentiation and fusion. Transcriptomic analysis revealed a loss in myogenic gene express...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422501380X |
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