Fusion FISH imaging: single-molecule detection of gene fusion transcripts in situ.

Double-stranded DNA breaks occur on a regular basis in the human genome as a consequence of genotoxic stress and errors during replication. Usually these breaks are rapidly and faithfully repaired, but occasionally different chromosomes, or different regions of the same chromosome, are fused to each...

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Bibliographic Details
Main Authors: Fatu Badiane Markey, William Ruezinsky, Sanjay Tyagi, Mona Batish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093488&type=printable
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