Development of a human tyrosinase activity inhibition assay using human melanoma cell lysate

Tyrosinase (TYR) inhibitors are required to treat skin hyperpigmentation. Currently live cell-based TYR assays and mushroom TYR in vitro assays are the common methods used to screen for TYR inhibitors. However, these methods are either time consuming and expensive or are not human TYR (hsTYR) specif...

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Bibliographic Details
Main Authors: Gengxuan Shi, Yunjiang Feng, Kathryn F. Tonissen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-11-01
Series:BioTechniques
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/07366205.2024.2441637
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