Enhancing radiation-induced reactive oxygen species generation through mitochondrial transplantation in human glioblastoma

Abstract Glioblastoma (GBM) is the most aggressive primary brain malignancy in adults, with high recurrence rates and resistance to standard therapies. This study explores mitochondrial transplantation as a novel method to enhance the radiobiological effect (RBE) of ionizing radiation (IR) by increa...

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Bibliographic Details
Main Authors: Kent L. Marshall, Murugesan Velayutham, Valery V. Khramtsov, Alan Mizener, Christopher P. Cifarelli
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-91331-2
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