ER-mitochondria tethering and its signaling: A novel therapeutic target in breast cancer

ER-mitochondria tethering and its signaling: A novel therapeutic target in breast cancer

Communication between the endoplasmic reticulum (ER) and mitochondria through mitochondria-associated ER membranes (MAMs) is assisted by tethering proteins and signaling pathways, manifesting the dynamic exchange of lipids, calcium, and signaling molecules. However, dysregulation of tethering and si...

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Bibliographic Details
Main Authors: Chamanthi Paidi, Yerusha Nuthalapati, Anuveda Sree Samudrala, Priyamvada Bhamidipati, Charanteja Mangam, Danny R. Welch, Ganji Purnachandra Nagaraju, RamaRao Malla
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Oncology
Subjects:
MT: Regular Issue
breast cancer
caveolin-1
ER-mitochondria tethering
ROS
YAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2950329925000645
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