Cyclodextrin-Based Drug Delivery Systems for Depression: Improving Antidepressant Bioavailability and Targeted Central Nervous System Delivery

Cyclodextrin (CD)-based drug delivery systems have emerged as a promising strategy to overcome limitations commonly encountered in antidepressant therapy, including low bioavailability, poor solubility, and suboptimal penetration of the blood–brain barrier. This review synthesizes current evidence d...

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Main Authors: Renata Maria Văruț, Alin Iulian Silviu Popescu, Simina Gaman, Carmen Elena Niculescu, Adrian Ștefan Niculescu, Dalia Dop, Mioara Desdemona Stepan, Nina Ionovici, Cristina Elena Singer, Cristina Popescu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/17/3/355
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